Experimental Induction of Allergic Contact Dermatitis in Sinclair, Hanford, and Yucatan Minipigs
Induction of allergic contact dermatitis in Sinclair, Hanford, and Yucatan minipigs demonstrated a consistent dermatitis-like response across all three lineages, although hydrocortisone did not reduce irritation.
Animal Models in Toxicologic Research: Pig
Chapter 20, In Haschek and Rousseaux's Handbook of Toxicologic Pathology (Fourth Edition). This chapter provides an overview of the use of pigs in toxicologic research, describes spontaneous pathology findings and key models of disease, and discusses animal welfare issues relevant to use of the pig in research.
A Changing Paradigm for Non-Rodent Species in Nonclinical Safety Studies: The miniature swine as an option in small and large molecule studies
The Altascientist Issue No. 32 - The choice of species for nonclinical safety studies is an important step in the drug development process.
Comparison of human, porcine & rodent wound healing with new miniature swine study data
This study compares wound healing characteristics across humans, traditional porcine models, rodent models, and new miniature swine, highlighting that pig skin more closely mirrors human skin in structure and healing by re-epithelialization rather than contraction. It also presents data showing that re-epithelialization rates in miniature swine vary with age and diabetic status, and concludes that miniature swine are a predictive and useful model for human wound healing research.
Characterization of transdermal pharmacokinetics of ketoprofen in Sinclair & Gottingen minipig
Comparison of transdermal ketoprofen pharmacokinetics in Sinclair and Göttingen minipigs demonstrated similar drug absorption and ADME profiles in both models.
No results found.