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Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations

Translational preclinical swine study data presented support the current finding that miniature swine are the animal model of choice for assessment of drug absorption, tolerance, and systemic toxicity following systemic exposures.

Pig Models for Gene Therapy: Prevalence of Adeno-associated Virus Neutralizing Antibodies in the Yucatan Miniature Swine and the Sinclair Nanopig

Gene therapy is a rapidly advancing field, with large animal models like non-human primates and miniature pigs playing a key role in evaluating the safety and effectiveness of AAV-based treatments due to their biological similarity to humans. This study focuses on measuring neutralizing antibodies to various AAV serotypes in different miniature swine cohorts, addressing a major limitation in translational research.
No results found.